Pfam 22.0 :: Home (KISTI)

Pfam 22.0 (June 2007, 9318 families)

Pfam is a large collection of multiple sequence alignments and hidden Markov models covering many common protein families. Pfam version 22.0 (June 2007) contains alignments and models for 9318 protein families, based on the Swissprot 51.7 and SP-TrEMBL 34.7 protein sequence databases.

Pfam is produced by the Pfam Consortium, a collaboration between researchers at the Wellcome Trust Sanger Institute near Cambridge UK, the Stockholm Bioinformatics Center at Stockholm University in Sweden, and HHMI Janelia Farm near Washington, DC in the US.

HELP	More information on Pfam, using this site, and the changes between Pfam releases.
PROTEIN SEARCH	Analyze a protein query sequence to find Pfam family matches.
DNA SEARCH	Analyze a DNA query sequence to find Pfam family matches. (Uses the GeneWise server at the Sanger Centre.)
BROWSE PFAM	View Pfam annotation and alignments.
KEYWORD SEARCH	Query Pfam by keywords.
TAXONOMY SEARCH	Find Pfam families by taxonomy.
BROWSE SWISSPFAM	View the domain organization of a SWISSPROT/TrEMBL sequence according to Pfam.

FTP downloads from Pfam

Browse the Pfam ftp site (Janelia Farm)
Release notes
Summary of changes from release 21.0 to 22.0, computer parsable
Pfam_ls - The PFAM HMM library, glocal alignment models.
Pfam_fs - The PFAM HMM library, local alignment models.
Pfam-A.full - The full alignments of the curated families.
Pfam-A.seed - The seed alignments of the curated families.
Pfam-B - PRODOM-generated alignments of sequence clusters in SWISSPROT and TrEMBL that are not modelled in the curated part of Pfam.
Pfam-C - Pfam Clans.
Swisspfam - The domain structure of SWISSPROT and TrEMBL proteins according to Pfam.
domain.pnh - A pseudo-new hampshire format tree file of Pfam families and sequences.
Janelia Farm Pfam server - a portable package for mirroring the Janelia Farm Pfam Web site (for instance, behind a corporate firewall).
Copyright notice for Pfam.
The full text of the GNU Library General Public License that Pfam is licensed under.