Pfam 22.0 :: Mac-1
Description of the Mac-1 family
Mab-21 <-- --> Macro

Mac-1


Accession number: PF09028
Mac 1

The bacterial protein Mac 1 adopts an alpha/beta fold, with 14 beta strands and 9 alpha helices. The N-terminal domain is made up predominantly of alpha helices, whereas the C-terminal domain consists predominantly of beta sheets. Mac 1 blocks polymorphonuclear opsonophagocytosis, inhibits the production of reactive oxygen species and contains IgG endopeptidase activity [1].

Description


Description text from InterPro entry IPR015117

Sequence information


Alignment

Seed (3)  Full (15)
Format:

Visualize domain structures

Seed (3)  Full (15)
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Species distribution

Tree depth:

Database References

INTERPRO IPR015117

HMMER build information

Pfam_ls [download HMM] Pfam_fs [download HMM]
Gathering cutoff 25.00 25.00 25.00 25.00
Trusted cutoff 317.40 317.40 39.50 464.90
Noise cutoff -67.10 -67.10 23.50 23.50
Build method of HMM hmmbuild -F HMM_ls SEED
hmmcalibrate --seed 0 HMM_ls
hmmbuild -f -F HMM_fs SEED
hmmcalibrate --seed 0 HMM_fs

Pfam specific information

Author of entryMistry J, Sammut SJ
Type definitionDomain
Source of seed memberspdb_2avw