Pfam 22.0 :: XPC-binding
Description of the XPC-binding family
XPA_N <-- --> XPG_I

XPC-binding


Accession number: PF09280
XPC-binding domain

Members of this family adopt a structure consisting of four alpha helices, arranged in an array. They bind specifically and directly to the xeroderma pigmentosum group C protein (XPC) to initiate nucleotide excision repair [1].

Description


Description text from InterPro entry IPR015360

Sequence information


Alignment

Seed (28)  Full (103)
Format:

Visualize domain structures

Seed (28)  Full (103)
display per page.

Species distribution

Tree depth:

Literature References

[1]
Solution structure and backbone dynamics of the XPC-binding domain of the human DNA repair protein hHR23B.
Kim B, Ryu KS, Kim HJ, Cho SJ, Choi BS;
FEBS J. 2005;272:2467-2476.

Database References

PFAMB
The following Pfam-B family may contain sequences that according to Prodom are members of this Pfam-A family.
PB174989
SCOP 1pve (family)
INTERPRO IPR015360

HMMER build information

Pfam_ls [download HMM] Pfam_fs [download HMM]
Gathering cutoff 27.60 27.60 22.30 22.30
Trusted cutoff 29.80 29.80 24.50 26.80
Noise cutoff 26.50 26.50 21.70 21.70
Build method of HMM hmmbuild -F HMM_ls SEED
hmmcalibrate --seed 0 HMM_ls
 hmmbuild -f -F HMM_fs SEED
hmmcalibrate --seed 0 HMM_fs

Pfam specific information

Author of entrySammut SJ
Type definitionDomain
Source of seed memberspdb_1pve