Pfam 22.0 :: 3D
Description of the 3D family
3Beta_HSD <-- --> 3H

3D


Accession number: PF06725
3D domain

This short presumed domain contains three conserved aspartate residues, hence the name 3D. It has been shown to be part of the catalytic double psi beta barrel domain of MltA [1].

Description

This short presumed domain contains three conserved aspartate residues, hence the name 3D. This conservation is suggestive of a cation binding function. The central aspartate is found in a DTG motif that is suggestive of a peptidase like active site.


Description text from InterPro entry IPR010611

Sequence information


Alignment

Seed (44)  Full (393)
Format:

Visualize domain structures

Seed (44)  Full (393)
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Species distribution

Tree depth:

Literature References

[1]
Crystal structure of MltA from Escherichia coli reveals a unique lytic transglycosylase fold.
van Straaten KE, Dijkstra BW, Vollmer W, Thunnissen AM;
J Mol Biol 2005;352:1068-1080.

Database References

PFAMB
The following Pfam-B families contain sequences that according to Prodom are members of this Pfam-A family.
PB145076 PB151233
INTERPRO IPR010611

HMMER build information

Pfam_ls [download HMM] Pfam_fs [download HMM]
Gathering cutoff 6.00 6.00 25.00 25.00
Trusted cutoff 6.40 6.40 25.20 25.20
Noise cutoff 4.20 4.20 22.50 22.50
Build method of HMM hmmbuild -F HMM_ls SEED
hmmcalibrate --seed 0 HMM_ls
 hmmbuild -f -F HMM_fs SEED
hmmcalibrate --seed 0 HMM_fs

Pfam specific information

Author of entryBateman A
Type definitionDomain
Source of seed membersBateman A